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Sep 2026

Simultaneous hydrophilic interaction liquid chromatography-tandem mass spectrometry quantification of serum neurotransmitters and related metabolites: Development, validation, and application to antenatal depression.

Serum neurotransmitter profiling is analytically challenging because the target panel includes highly polar compounds with markedly different ionization behaviors, while several catecholamine-related analytes are also susceptible to oxidation during thawing and handling. Here, we developed and validated a derivatizatio...

Rui Guo, Miao Zhu, Fei Huang et al. · 0 citations
Review Open access 2026

The dual role of ion channels in diabetic kidney disease: a translational paradigm for biomarkers and target discovery - reviews and prospects.

This review systematically elucidate how hyperglycemia, oxidative stress, and inflammation disrupt sodium, calcium, potassium, and chloride channel networks through interconnected pathways such as AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR), NLR family pyrin domain containing 3 (NLRP3), and...

Xi Xiong, Bao Yan, Bin Ke et al. · 0 citations

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