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Guang-Shi Du

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Sep 2026

Integrated reverse network toxicology and experimental validation identify PTP4A3 as a key target of Benzo[a]pyrene in prostate cancer.

It is suggested that benzo[a]pyrene could contribute to the acquisition of pro-invasive phenotypes in prostate epithelial cells and potentially to prostate carcinogenesis, probably through upregulating PTP4A3 to activate matrix remodeling programs.

Shi-Wang Yuan, Jian Shi, Lin Jiang et al. · 0 citations

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