Author

Guang Liang

3 papers indexed here

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Open access Oct 2026

Cardiomyocyte-enriched OTUD5 alleviates pathological myocardial hypertrophy by deubiquitinating STAT3 and modulating the STAT3-PGC-1α axis.

Pathological cardiac hypertrophy presents a important public health challenge, particularly in aging populations, highlighting the urgent need for novel therapeutic targets. This study investigates the role and molecular mechanisms of OTUD5 in pathological cardiac hypertrophy. OTUD5 expression is greatly increased in c...

Bo-Zhi Ye, Yu-Cheng Jiang, Zhao-Zheng Zheng et al. · Experimental and Molecular M... · 0 citations

Sep 2026

The deubiquitinase YOD1 in renal tubular epithelial cells promotes diabetic kidney disease by stabilizing KEAP1.

It is demonstrated that the YOD1-KEAP1 axis mediates oxidative stress injury in RTECs and highlight that targeting YOD1 represents a potential treatment approach for DKD.

Qing-Qing Zhao, Ying Zhao, Shi-Jie Fan et al. · Acta Pharmacologica Sinica · 0 citations

Aug 2026

A ternary zein/soy lecithin/dextran sulfate nanocarrier for improved resveratrol bioactivity delivery: Enhanced solubility, stability, and bioactivity.

Resveratrol (RES), a natural compound widely used as a food additive and preservative, exhibits anti-inflammatory and antioxidant activities. However, its poor solubility and stability severely limit its translational potential for clinical applications. To address these challenges, we developed a core-shell nanopartic...

Zhen-Yao Wu, Wen-Qi Wu, Wu Luo et al. · International Journal of Bio... · 0 citations