Author

Guan-Yu Chen

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Open access Sep 2026

Synthesis of RARα–PROTAC and its delivery via Polygonatum sibiricum exosome-like nanoparticles for the treatment of colorectal cancer

These findings provide a feasible strategy for degrading RARα in CRC and highlight the potential of plant-derived exosome-like nanoparticles as efficient carriers for PROTAC delivery, indicating a new direction for targeted cancer therapy.

Geng-Zheng Zhu, Yan-Ping Zhao, Ming-Zhu Chen et al. · Materials Today Bio · 0 citations