Author

Guan-Yi Li

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Open access Aug 2026

Identification of YL064 as a novel inhibitor of ATXN3 to suppress tumor growth and metastasis by promoting degradation of oncogenic substrates

YL064 is established as a promising ATXN3 inhibitor that targets the ubiquitin-proteasome pathway to exert anti-tumor effects, highlighting its potential as a novel therapeutic agent for ATXN3-driven cancers.

Zhenge Zhang, Wenhui Bai, Yayue Tan et al. · Cell Death & Disease · 0 citations