Hypervirulent Klebsiella pneumoniae (hvKp) infection often induces sepsis characterised by remarkable phenotypic and functional diversity among neutrophils. However, the roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single-cell RNA sequencing, we ide...
Neutrophils are increasingly recognized as key regulators of autoimmune responses; however, the mechanisms by which their heterogeneity is influenced across various tissues in autoimmunity remain insufficiently understood. Here, using experimental autoimmune encephalomyelitis (EAE), we show that splenic and bone marrow...
Qian-Ling Jiang, Gao-Chen Zhu, Wen Si et al.· Journal of Autoimmunity· 0 citations
Rapid on-site detection of bacterial contamination remains an urgent need in public health and environmental monitoring. Herein, we report a one-step, label-free colorimetric sensor for broad-spectrum bacterial detection based on a competitive electrostatic mechanism. Cationic poly-l-lysine (PLL) induces the aggregatio...