Review
Open access
Aug 2026
From PEG to randomized PEG: a macromolecular strategy tackling PEG immunogenicity.
PEGylation is a crucial strategy in modern nanomedicine, offering effective and safer therapeutics. However, the growing prevalence of anti-PEG antibodies (APAs) in patients has raised critical concerns, with multiple studies demonstrating reduced clinical efficacy and safety risks associated with APA formation. This h...
Julian Schmidt, Caroline Bockhard, Lea Simon et al.
· Advanced Drug Delivery Revie... · 0 citations