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Author

Gregg A. Duncan

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Open access Oct 2026

Lung surfactants as a component of lipid nanoparticles for pulmonary mRNA delivery.

Pulmonary delivery of lipid nanoparticles (LNPs) remains an area of significant interest, given the broad range of genetic disorders that could be addressed through localized administration of therapeutic nucleic acids to the lung. In this study, we investigated how incorporation of the clinically used lung surfactant...

Sarah S. Nasr, Owen E. Tabah, Sahana Kumar et al. · 0 citations
Open access Jun 2026

Liquid crystalline mesophase spacing as a quantitative predictor of release kinetics for co-loaded hydrophilic and hydrophobic payloads

Synchrotron SAXS establishes characteristic repeat spacing as a quantitative structural metric directly governing hydrophilic release kinetics, providing a rational design framework linking mesophase architecture to functional performance across a range of payload structures.

S. R. Dasaro, Shruti S Sawant, Alexa Stern et al. · 0 citations

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