Open access
Sep 2026
Live-cell DNMT3A “catalysome” mapping using engineered methyl-transfer pathways
Abstract Catalytic interplay among three major DNA methyltransferases (DNMTs) establishes and maintains genomic modification patterns that define mammalian cell identity and transitions during development. Despite extensive molecular characterization, mechanisms and precise contributions of DNMT-specific methylation in...
V. Stankevičius, Liepa Gasiulė, Kotryna Kvederavičiu̅tė et al.
· Nucleic Acids Research · 0 citations