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Grace M. Schlichting

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#protein folding Open access Oct 2026

Structure and Function of Archaeal SRP54 Protein Mutants Associated with Human Severe Congenital Neutropenia

SRP54, a key component of the signal recognition particle, is a highly conserved enzyme both structurally and functionally. The protein plays a vital role in cellular protein translocation by interacting with the translating ribosome and a membrane receptor, thereby aiding protein folding and trafficking. Recent stud...

Ming Yang, Andrew D. Brim, Lawton F. Long et al. · 0 citations

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