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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Gowri Nayar

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Open access Aug 2026

Homology-Based Variant-Effect Predictors Break Down on Cytochrome P450 Pharmacogenes

Drawing on evidence that a variant’s effect can depend on the drug, it is hypothesized that substrate identity is the key missing feature in current models, and that predicting function for these multi-substrate enzymes may require redefining function as substrate-conditioned.

Helen Z. Xu, I. Samori, Gowri Nayar et al. · 0 citations
Open access Aug 2026

Interpreting Protein Language Models: high attention sites predict functional regions

The utility of HA sites for suggesting candidate binding sites and the biological interpretability of PLM representations is explored, demonstrating the biological interpretability of PLM representations and offers a valuable method to prioritize functionally relevant protein residues for targeted biomedical research.

Sophia J. Pribus, Russ B. Altman, Gowri Nayar · 0 citations

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