Solid-Acid Catalyzed Acylation of Bio-Based Furan to 2-Acetylfuran: Mechanistic Insights into Selectivity Loss and Catalyst Deactivation Kinetics
Furan is an important biorefinery platform molecule, and its Friedel–Crafts acylation with acetic anhydride (Ac2O) to yield 2-acetylfuran (AF) is a commercially relevant transformation with applications in pharmaceuticals and flavoring. However, developing solid-acid catalysts for this reaction is challenging owing t...