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Author

Giulia Tetè

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Review Open access Oct 2026

The PI3K/AKT/mTOR Pathway Is a Major Intracellular Regulator of Mast Cells Implicated in the Gut–Brain Axis and Mediates Inflammation

Phosphoinositide 3-kinase beta (PI3Kβ), phosphatidylinositol (3,4,5)-trisphosphate (PIP3), and phosphatase and TENsin homolog (PTEN) play crucial roles in the remodelling of cell junctions during infection. Remodelling of epithelial and endothelial junctions is a physiological effect aimed at maintaining barrier integr...

P. Conti, F. Mastrangelo, Armando Coppola et al. · 0 citations

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