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Giulia Lodigiani

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Review Open access Aug 2026

Nature-inspired macrocyclic peptides: Discovery and molecular engineering for drug development.

Natural cyclic peptides have long served as a rich reservoir of bioactivity, occupying a unique region of the drug space that bridges the gap between small molecules and large biologics, and researchers are rationally engineering next-generation macrocycles, positioning them at the frontier of modern drug development.

Greta Bergamaschi, Giulia Lodigiani, Stefano Gandolfi et al. · 0 citations

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