Author

Giselle M. Boukhaled

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Open access Oct 2026

Investigating the association between interferons and flares of systemic lupus erythematosus at a single cell level

Elevated levels of interferons (IFN) are a hallmark of Systemic Lupus Erythematosus (SLE) and are linked to disease flares, but the precise mechanisms underlying this remain unclear. We examined the association between IFN-stimulated proteins (ISPs) and immune changes in flaring and quiescent SLE patients at single...

Zoha Faheem, Giselle M. Boukhaled, Carol Nassar et al. · Frontiers in Immunology · 0 citations

Aug 2026

CAR T Cells Targeting an Intracellular Leukemia Antigen Promiscuously Presented by Diverse HLA-II Alleles.

Chimeric antigen receptor (CAR) technology has revolutionized B-cell malignancy treatment by enabling T cells to effectively recognize and target lineage-specific surface antigens. However, CAR T cells show limited efficacy against myeloid neoplasms and solid tumors due to challenges in identifying suitable surface tar...

Evey Y F Zheng, Chung-Hsi Wang, T. Ochi et al. · Blood Cancer Discovery · 0 citations