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Author

Gisela Gabernet

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Open access Sep 2026

Transcriptomic characterization of transitional B cells reveals four subsets with perturbed activation profiles in scleroderma

Summary We previously demonstrated that patients with scleroderma or systemic sclerosis (SSc) have elevated autoreactive transitional B cells, including against topoisomerase I (anti-topoisomerase I autoantibody [ATA+]). This suggests that defective transitional B cell tolerance could drive autoimmunity in SSc. To inve...

Claire F. Beesley, Nina R. Goldman, Gisela Gabernet et al. · 0 citations
Open access Jul 2026

The Immune Signatures Data Resource 2.0: An Expanded Compendium of Systems Vaccinology Datasets 2304506

An expanded and standardized framework that harmonizes human systems vaccinology datasets using ImmPort metadata, and develops an automated pipeline to integrate experimental design, clinical metadata and serological response data from ImmPort with linked transcriptional profiling data from GEO is presented.

Jian Xing, Gisela Gabernet, Anthony Melillo et al. · 0 citations

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