The unmet need for long-acting, narrow-spectrum antibiotics: a narrative review and call to action for antimicrobial stewardship
Abstract Long-acting lipoglycopeptides (laLGPs) are classified as Reserve agents under the WHO AWaRe framework, yet they are increasingly used as consolidation and suppressive therapy for Gram-positive bacteremia, endocarditis, and device-related infection caused by organisms that remain fully susceptible to first-line...