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Review Open access Sep 2026

RBM15 in leukemogenesis: an emerging regulator at the interface of RNA biology and hematopoiesis

RNA-binding motif protein 15 (RBM15) is a key regulator of hematopoiesis and leukemogenesis, linking RNA metabolism, epitranscriptomic regulation, and lineage specification. Identified through the RBM15::MKL1 fusion in acute megakaryoblastic leukemia (AMKL), RBM15 functions within the N6-methyladenosine (m6A) writer co...

Jether Amos Espinosa, Madeline Y. Mayday, Abigail R. Robb et al. · 0 citations
Open access Aug 2026

RUNX1T1 drives stem-like small-cell neuroendocrine prostate cancer identity

It is found that RUNX1T1 is essential for SCNPC survival, as its knockdown induced apoptotic cell death and the acquisition of PRAD-like identity, including alterations in genes involved in cell-cell adhesion and epithelial cell polarity are found.

Zi-Qin Wang, H. Jung, Changhyeon Hong et al. · 0 citations

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