CD44-targeted hyaluronic acid nanohydrogels enhance macrophage uptake and preserve the anti-inflammatory efficacy of dexamethasone.
The inflammatory response is among the most critical drivers of tissue damage and systemic dysfunction. Although corticosteroids (CS) can achieve symptom remission and prevent tissue damage, systemic side effects are an issue due to the lack of targeted drug delivery. To this end, we propose a new approach to deliverin...