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Author

Ghulam Jeelani

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Sep 2026

Tonakiamides A and B, Antitrypanosomal Lipopeptides Isolated from a Marine Okeania sp. Cyanobacterium

The structure elucidation of peptidic natural products is often hindered by extensive N-methylation and repetitive sequence motifs, which complicate NMR spectral analysis. Tonakiamides A and B (1 and 2), two lipopeptides isolated from a marine Okeania sp. cyanobacterium collected in Japan, represent such challenging...

Natsumi Watanabe, Ghulam Jeelani, Tomoyoshi Nozaki et al. · 0 citations
Open access Aug 2026

Unraveling the role of glucosamine: Fructose-6-phosphate aminotransferase (GFAT) in Entamoeba histolytica: A comprehensive exploration through biochemical, reverse genetic, and Metabolomic analyses.

It is demonstrated that GFAT plays an important role in the hexosamine biosynthetic pathway, trophozoite proliferation, and efficient encystation in Entamoeba, and supports its further evaluation as a potential therapeutic target for amebiasis.

Ghulam Jeelani, Farida Ifadotunnikmah, Tomoyoshi Nozaki · 0 citations

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