Autoimmune and autoinflammatory disorders can exhibit significant clinical and immunological overlap, often leading to diagnostic delays and therapeutic misdirection. Polyclonal hypergammaglobulinemia and antinuclear antibodies (ANA), although classically associated with autoimmune processes, have been occasionally rep...
Ghalia Khellaf, A. Benziane· International Journal of Adv...· 0 citations
Background/Objectives: Multicentric Castleman disease (MCD) is a rare systemic lymphoproliferative disorder driven by interleukin-6 (IL-6) dysregulation and frequently associated with human herpesvirus 8 (HHV-8) infection. AA amyloidosis is a severe complication of chronic inflammatory states, resulting from extracellu...
Ghalia Khellaf, Zoheir Benzekri, Djenatte Hakem et al.· International Journal of Adv...· 0 citations
Background: Wolfram syndrome is a rare autosomal recessive neurodegenerative disorder characterized by juvenile-onset diabetes mellitus, optic atrophy, diabetes insipidus, sensorineural deafness, and progressive neurological deterioration. The diagnosis is often delayed due to the sequential appearance of clinical mani...
Ghalia Khellaf, M. Benabadji· International Journal of Adv...· 0 citations
Background: Neurofibromatosis Type 1 (NF1) is an autosomal dominant neurocutaneous disorder. Renal complications include renovascular hypertension. We report a case diagnosed in a nephrology setting after a 14 year delay.
Case presentation: A 27 year old woman with severe hypertension, acute myeloid leukemia (treated w...
Ghalia Khellaf, H. Sahel, A. Benziane· International Journal of Adv...· 0 citations
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