Preclinical and clinical evaluation of systemic danegaptide for the treatment of nonproliferative diabetic retinopathy.
Nonproliferative diabetic retinopathy (NPDR) is a serious and vision-threatening manifestation of diabetic eye disease. Most patients with diabetic eye disease have NPDR. Intravitreal vascular endothelial growth factor (VEGF)-neutralizing agents are able to suppress increased vascular leakage caused by poor glycemic co...