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Geraldine McCarthy

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Review Open access Sep 2026

The pharmacotherapeutic use of clozapine in older adults: A narrative review

Clozapine remains the gold-standard treatment for refractory schizophrenia, yet its use in older adults is often limited by concerns regarding tolerability, age-related pharmacokinetic changes, and the burden of medical comorbidities. This narrative review synthesises current evidence on clozapine use in older populati...

Kate Mulholland, Brian O'Donoghue, D. Siskind et al. · 0 citations

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