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Gerald F. Joyce

1 paper indexed here

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Open access Aug 2026

Structure of an RNA polymerase ribozyme replication complex

The structure of such a polymerase ribozyme bound to RNA substrates comprising the template, primer, and nucleoside triphosphate (NTP) analog is presented, revealing how directed evolution shaped flanking elements around a highly conserved catalytic core derived from the ancestral class I ligase ribozyme.

Timothy S. Strutzenberg, David P. Horning, Wesley G. Cochrane et al. · 0 citations

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