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Author

Gengting Dong

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Oct 2026

The preventive effects of tetrahydroberberine on male obese mice and its uptake by adipocytes are associated with the D2R-PI3K axis and OCT2.

Obesity arises from a chronic imbalance between energy intake and consumption that culminates in pathological adipose tissue expansion, ectopic lipid deposition, and persistent low-grade inflammation. Tetrahydroberberine, the principal reductive metabolite of berberine, exhibits potent lipid-lowering and fat-targeting...

Zi-Wen Li, Chu-Rou Huang, Yong-Qing Chen et al. · 0 citations
Open access Jul 2026

Cimicifuga foetida L. polysaccharide alleviates ulcerative colitis by inhibiting pyroptosis and regulating gut microbiota

The preliminary biological assessment suggests that the polysaccharide subfraction SM05 alleviated the symptoms of UC induced by DSS, and may be related to the activation of the Nrf2/Keap1 pathway, the inhibition of pyroptosis, and the regulation of the intestinal microbiota.

Qing Luo, Yangyang Xu, Zhihua Li et al. · 0 citations

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