Genxi Li

Copper-Peptide Assemblies with Self-Driven Signal Release for Electrochemical Analysis of Exosomes

Multifunctional peptides have garnered considerable attention owing to their excellent biocompatibility and unique physicochemical properties. Herein, we report an electrochemical method for the sensitive detection of exosomes based on copper-peptide assemblies with a self-driven signal release approach. In the desig...

Target-Triggered Molecular Domino Effect: A Programmable Peptide Self-Assembly Induced Signal Amplification System.

In nature, biological systems achieve highly efficient sensing through the orchestrated self-assembly of proteins, which converts subtle molecular stimuli into clear physiological responses. However, replicating such high-fidelity transduction in artificial peptide-based sensors remains a challenge. Herein, we report a...

Cleavage Activity Adjustment of the CRISPR/Cas System for Enhanced Diagnostics.

An electrochemical biosensor integrating self-propelled nanocarriers with DNA cascade amplification strategy for ultrasensitive PPIA detection.

An electrochemical biosensor that integrates self-propelled nanocarriers with DNA cascade amplification strategy for ultrasensitive PPIA detection and exhibits excellent specificity and performs reliably in clinical lung adenocarcinoma serum specimens, demonstrating its promising applicability for early diagnosis of th...