Author

Gangshun Yi

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Open access Jul 2026

Structural dynamics of RNA polymerase II throughout the nucleotide addition cycle

These findings define a comprehensive structural and dynamic framework for RNAPII NAC, yielding a “molecular movie” of RNAPII in action and revealing a fundamental principle by which the enzyme balances speed and fidelity through coordinated conformational dynamics.

Gangshun Yi, Qing-Rong Li, H. Holmberg et al. · Nature Communications · 1 citation