Sep 2026
Integrative network toxicology and virtual knockout analysis suggest TSNA-associated molecular features in large cell neuroendocrine carcinoma.
A hypothesis-generating computational model in which TSNA-associated target networks converge on PI3K-Akt-related signaling and the IGFBP2/EDNRB expression axis in LCNEC is proposed, which may inform future experimental studies on TSNA-related lung cancer biology and potential biomarker discovery.
Zhe Xiong, Liu-Zhe Yin, Jia-Hui Yu et al.
· Computational biology and ch... · 0 citations