Open access
Sep 2026
Coordinated cellular programmes distinguish responses to neoadjuvant PD-L1 blockade and potentiate combinatorial immunotherapy in ESCC.
BACKGROUND Programmed death ligand 1 (PD-L1) blockade offers new therapeutic options for oesophageal squamous cell carcinoma (ESCC); however, the underlying mechanisms and associated biomarkers that determine treatment response remain unclear. OBJECTIVE We delineate the mechanisms underlying the response and resistan...
Si Li, Ji-Yu Guo, Jian-Qun Ma et al.
· Gut · 0 citations