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Sep 2026

A Metabolic Nanoplatform Potentiates Triple-Negative Breast Cancer Radiosensitivity via Disrupting Carbonic Anhydrase IX/Pentose Phosphate Pathway Crosstalk

Radiotherapy resistance in tumors driven by metabolic adaptations within acidic microenvironments involves the upregulation of both carbonic anhydrase IX (CA IX) and the pentose phosphate pathway (PPP) as well as the functional crosstalk between them. To overcome this, we developed a polyvinylpyrrolidone (PVP)-modifi...

Zhi-Li Ma, Bin Zhao, Yun Wang et al. · 0 citations
Review Sep 2026

Emerging biodegradable nanomaterials for innovative tumor immunotherapy.

Immunotherapy has rapidly emerged as the new pillar of cancer treatment alongside surgery, radiotherapy and chemotherapy. However, existing immunotherapeutic approaches face significant limitations such as inefficient tumor-targeted drug delivery, poor cellular internalization and off-target effects, all of which lead...

Ru-Tuan Dong, Shuai-Shuai Ding, Bo-Kai Song et al. · 0 citations

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