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Author

Gaia Pigino

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Review Sep 2026

Primary cilia: master conductors of cellular communication in development and disease.

Emerging evidence indicates that cell-type-specific and temporally dynamic ciliary signatures determine signalling competence and disease susceptibility, and defining these signatures and the mechanisms that regulate their plasticity could lead to new therapeutic opportunities for ciliopathies and other cilia-associate...

O. K. Thomsen, Gaia Pigino, L. B. Pedersen et al. · 0 citations
Open access 2026

Reconstituting the Motility of Intraflagellar Transport Trains Ex Vivo.

Intraflagellar transport (IFT) is essential for the assembly, maintenance and function of most eukaryotic cilia. It acts as a bidirectional cargo transport system, powered by kinesin and dynein motors to navigate through the crowded ciliary environment. Here, we describe a method to isolate intact IFT trains from live...

Aditya Chhatre, L. Štěpánek, S. Diez et al. · 0 citations

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