Gabriela Nestal de Moraes

Neutrophil extracellular traps induce chemoresistance in human breast cancer cells through the PI3K/AKT/NF-κB pathway

Introduction Breast cancer is the most common malignancy and the leading cause of cancer-related mortality among women, and resistance to chemotherapy remains a major clinical challenge. Although doxorubicin is widely used, its efficacy is limited by chemoresistance. Neutrophil extracellular traps (NETs), web-like stru...