The Impact of Renin-Angiotensin Aldosterone System Inhibitors in IgA Nephropathy: A Meta-Analysis of Randomized Controlled Trials.
Treatment with maximally tolerated RAASi alone does not sufficiently slow the rate of eGFR decline in high-risk patients with IgAN, leaving patients at risk for ESKD, and underscore the need for disease-modifying therapies capable of effectively preserving kidney function, particularly in this predominantly young patie...