Gabriel Herrera-López

Age-related electrophysiological changes in layer 5 pyramidal cells and interneurons of the rat medial prefrontal cortex.

Overall, aging differentially disrupts excitability and ionic mechanisms in pyramidal and interneuron populations, leading to impaired synaptic integration and altered short-term plasticity in mPFC microcircuits, suggesting that disrupted synaptic integration and intrinsic neuronal function in the aged neocortex may co...