G. Zadra

From Tissue Specificity to Systemic Cues: Shaping MYC‑Driven Tumor Metabolism.

The proto-oncogene MYC acts as a master regulator of diverse metabolic programs that fuel tumor initiation and progression, but the exact programs it activates depend heavily on context, tissue type, accompanying mutations, and the tumor microenvironment (TME). Furthermore, extrinsic influences, including diet and syst...