Open access
Aug 2026
Deep phenotyping and multi-omics analyses reveal systems-wide metabolic dysregulation in a refined trisomy mouse model of Down syndrome
Deep phenotyping and multi-omics analyses showed that Ts66Yah mice develop pronounced and widespread metabolic disturbances, establishing Ts66Yah as a valuable reference model for the mechanistic and comparative study of metabolic dysfunction in DS.
Muzna Saqib, Fangluo Chen, Diya K. Mistri et al.
· bioRxiv · 0 citations