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Author

G. Wallmann

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Open access Sep 2026

AlphaPeptTools: scverse-native analysis of mass spectrometry-based proteomics

Mass spectrometry (MS)-based proteomics now routinely profiles proteomes at scale, but extracting biological insight and integrating complementary modalities remains challenging. Here, we present AlphaPeptTools, a Python package for the analysis of MS-proteomics data built on the AnnData data structure of the scverse....

Vincenth Brennsteiner, L. Diedrich, S. Ben-Moshe et al. · 0 citations
Open access Oct 2026

SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening.

Forward genetic screening links genotype to phenotype by introducing random genetic perturbations and identifying phenotype-altering mutations. Although genome-scale screens are routine for simple phenotypes in cultured cells, extending them to complex image-based phenotypes remains challenging. Here, we present spatia...

Niklas A. Schmacke, Sophia C. Mädler, G. Wallmann et al. · 0 citations

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