Author

G. Piel

2 papers indexed here

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Open access Sep 2026

INPP5K limits PtdIns (4,5)P2 accumulation in CD19 microclusters and restrains CD19 co-receptor membrane proximity and BCR-proximal signaling in B cells

Introduction CD19 is a key B-cell co-receptor that amplifies B-cell receptor (BCR) signaling and tunes B-cell activation thresholds. How the conformation of the CD19 cytoplasmic domain is regulated to restrain basal and BCR-induced signaling remains incompletely understood. We investigated whether the phosphoinositide...

Bastien Möes, Alice Mostafa, R. Malempré et al. · Frontiers in Immunology · 0 citations

Review Open access Jul 2026

Next-generation stealth lipid-based nanocarriers: advances in PEGylation and emerging amide-containing polymer alternatives.

Stealth strategies for lipid nanocarriers, focusing on liposomes and LNPs are reviewed, and PEG engineering with selected amide-based polymer alternatives are compared and related to practical manufacturing factors, synthetic feasibility and the tunability of lipid-polymer conjugates are related.

Manon Degey, Stefano Pedergnana, B. Evrard et al. · Nanomedicine · 0 citations