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Open access Sep 2026

Microbial-Derived Daidzin (Eco-3) Suppresses RANKL-Induced Osteoclastogenesis by Targeting the TBK1–NFATc1 Signaling Axis

Eco-3, a microbial-derived daidzin, has been reported to possess diverse biological activities; however, its effects on osteoclast differentiation and the underlying molecular mechanisms remain unclear. In the present study, we investigated the effects of Eco-3 on receptor activator of nuclear factor-κB ligand (RANKL)-...

Nivethasri Lakshmana Perumal, Kyung-Bon Koo, G. Park et al. · 0 citations

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