Differential Expression of ACAN, COL1A1, and COL2A1 in Cartilage and Synovium During Osteoarthritis Progression: An Observational Pilot Study Supported by Preliminary Bioinformatic Analysis
Background: Osteoarthritis (OA) patients experience poorer quality of life due to persistent symptoms and chronic pain. Unfortunately, the molecular basis of OA development is poorly understood, thus posing a major challenge for therapeutic interventions. The aim of this study was to compare the expression of genes enc...