Author

G. Mantini

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Open access Sep 2026

Human amniotic mesenchymal stromal cell-derived extracellular vesicles reprogram microglia and prevent neurodegeneration in experimental models of Alzheimer’s disease

HAMSC-EVs exert robust anti-inflammatory and neuroprotective effects in both murine and human AD models, improving cognition, modulating glial activation, and restoring synaptic integrity, and highlight the translational potential of intranasal hAMSC-EVs as an adjuvant therapeutic strategy targeting neuro inflammation...

Andrea Papait, F. Natale, A. Silini et al. · Translational Neurodegenerat... · 0 citations

Open access Jul 2026

Rare AFG3L2 and POLG Variants Suggest a Role for Mitochondrial Dysfunction in Enteric Neuronal Vulnerability in Idiopathic Achalasia

Findings support a potential link between mitochondrial dysfunction, enteric neurodegeneration, and idiopathic achalasia and rare mitochondrial-related variants may contribute to disease susceptibility in selected individuals by increasing vulnerability of inhibitory enteric neurons, although functional validation and...

A. Latiano, F. Tavano, L. Micale et al. · International Journal of Mol... · 0 citations