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Author

G. Lynch

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Open access Aug 2026

Optimized parameters for CRISPR-Cas9 interference library design.

This work compares the performance of multiple KRAB domain systems, develops an updated CRISPRi-specific on-target scoring scheme, and quantitatively characterize off-target effects associated with seed-sequence patterns.

Smriti Srikanth, Fengyi Zheng, Laura M Drepanos et al. · 0 citations

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