Author

G. Kalpouzos

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Open access Aug 2026

Impact of brain and blood iron on glial density in aging, and relations to cognition: evidence from a 5-year longitudinal multimodal MRI-PET study.

It is suggested that higher local subcortical iron accumulation contributes to low-grade neuroinflammation in middle-aged and older adults, but only brain iron accounts for cognitive and motor decline, indicating that low-grade neuroinflammation may partly constitute an adaptive response to the deleterious effects of i...

G. Kalpouzos, F. Falahati, Jonatan Malmros et al. · Brain, behavior, and immunit... · 0 citations

Open access Jul 2026

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community.

In cognitively unimpaired older adults, elevated blood p-tau217 was linked to faster shrinkage in AD-specific brain regions, whereas NfL and GFAP were associated with more widespread atrophy, with NfL also associated with accelerated WMH accumulation.

Martina Valletta, D. L. Vetrano, E. J. Laukka et al. · Annals of Neurology · 0 citations