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Review Open access Oct 2026

Biological Variability and Biomedical Innovation in Personalized Orthodontics: A Systematic Review with Narrative Synthesis

Background/Objectives: Orthodontic treatment response varies considerably among patients because mechanical loading interacts with individual biological, anatomical, systemic, and behavioral characteristics. Advances in mechanobiology, molecular biomarkers, omics technologies, and artificial intelligence (AI) may suppo...

S. La Rosa, R. Leonardi, Vincenzo D'Antò et al. · 0 citations
Review Open access Oct 2026

Clinical and Genetic Characterization of a Family with Tooth Agenesis Carrying a Novel LEF1 Variant

Background: Tooth agenesis is one of the most common developmental anomalies of the human dentition and may occur either as an isolated trait or as part of a syndromic condition. Advances in genomic technologies have facilitated the identification of genes involved in odontogenesis, including LEF1 (Lymphoid Enhancer-Bi...

Ludovica Fortuna, Roberto Bertozzi, V. Trevisan et al. · 0 citations

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