Summary Paragraph Personality traits describe stable differences in how people think, feel, and behave and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustness, generalizability,...
T. Schwaba, Margaret L. Clapp Sullivan, W. Akingbuwa et al.· Nature· 5 citations· ⚡1
This work proposes a framework for identifying confounders of two non-causally related traits by employing cross-trait pleiotropy analysis to detect genetic loci that affect both traits and multi-trait colocalisation to identify molecular phenotypes mediating these effects.
J. Yarmolinsky, F. Cavallo, F. Koskeridis et al.· medRxiv· 0 citations
Some of the advantages of familial data using the Norwegian Mother, Father and Child Cohort Study (MoBa), a population-based cohort of parents and offspring with extensive genotype data, are illustrated along with broad and longitudinal phenotyping of health and functioning.
E. Corfield, A. Shadrin, O. Frei et al.· Nature· 3 citations
The results suggest that population-level associations of asthma with psychosis spectrum conditions could be due to shared molecular mechanisms involving fatty acid metabolism, ion channel activity, and iron homeostasis.
C. Dardani, J. W. Robinson, A. Havdahl et al.· Biological Psychiatry· 0 citations
Little evidence that maternal smoking initiation affected WHR is found, and little evidence that maternal smoking heaviness affected the remaining cardiometabolic risk factors; paternal smoking showed no clear effect on any outcome.
G. Power, T. Bond, L. Bhatta et al.· BMC Medicine· 0 citations
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