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Open access Oct 2026

Population-based assessment of treatment patterns for high-risk localized prostate cancer

Introduction: High- and very high-risk (H/vHR) localized and locally advanced prostate cancer (LPCa) carry a high burden of distant relapse. In light of emerging data on adjunctive systemic therapy, we aimed to assess present-day, real-world treatment patterns and outcomes among Canadian patients with intermediate-risk...

C. Wallis, Shawn Malone, I. Cagiannos et al. · 0 citations
Open access Sep 2026

Impact of BRCA alterations on Androgen Receptor pathway inhibition treatment outcome in advanced prostate cancer.

Androgen Receptor Pathway Inhibitors (ARPIs) are frequently used to treat advanced prostate cancer (PCa). Understanding the impact of homologous recombination repair (HRR) alterations on ARPI treatment outcomes is critical for optimizing treatment. We conducted a retrospective analysis of pooled data from five randomiz...

Ruchi Chaudhary, Karen A. Urtishak, M. Gormley et al. · 0 citations

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