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Author

G. Gonnella

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2 papers indexed here

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Open access Oct 2026

Articular Cartilage-Derived Extracellular Matrix Material Promotes a Pro-Regenerative Macrophage Phenotype to Support Chondrogenesis.

Articular cartilage (AC) repair remains a major clinical challenge due to its limited healing capacity and the inability of current treatment strategies to restore long-term function. Biomaterial-based strategies which support favorable immune responses and appropriate progenitor cell function have shown promise in enh...

S. O'Rourke, G. Gonnella, G. S. Kronemberger et al. · 0 citations
Open access Sep 2026

Multilayered extracellular matrix–derived scaffolds direct progenitor cell differentiation in vitro and osteochondral-tissue formation in vivo

Osteochondral repair requires restoration of zonally organised articular cartilage and subchondral bone, yet translatable implants rarely reproduce this spatial complexity. Here, we developed an acellular multilayer scaffold comprising a superficial 2% (w/v) articular cartilage extracellular matrix (AC-ECM) phase, an i...

G. Gonnella, O. Strong, V. M. Sularea et al. · 0 citations

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