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Author

G. Duruksu

2 papers indexed here

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Oct 2026

Early preventive effects of a Cathepsin S inhibitor on inflammation in a rat model of endotoxin-induced uveitis.

OBJECTIVES Uveitis, an inflammation of the uveal tissue, can cause permanent vision loss. A previous study revealed elevated levels of cathepsin S in the tear proteomic analyses of patients with juvenile idiopathic arthritis-associated uveitis. This study investigates the effects of a cathepsin S inhibitor on inflammat...

Büşra Yılmaz Tuğan, S. S. Gocmez, G. Duruksu et al. · 0 citations
Aug 2026

IL-1β-induced inflammatory stress modulates mitochondrial and metabolic gene expression in dermal fibroblasts

It is demonstrated that IL-1β induces mitochondrial dysfunction in dermal fibroblasts and establish a reliable inflammatory model for investigating mitochondrial mechanisms involved in skin aging, chronic wound healing, and other inflammation-related skin disorders.

Candan Altuntaş, Nelin Hacıoğlu, G. Duruksu et al. · 0 citations

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