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MT networks position cellularization furrows to accurately partition multinucleate Sphaeroforma arctica. U-ExM, perturbations, and live imaging suggest shared patterns of cytoskeletal remodeling in eukaryotes.
The conserved membrane protein Chloride Channel CLIC-like protein 1 (CLCC1) is identified as a Torsin1A interaction partner whose absence phenocopies membrane fusion defects caused by Torsin deletion inform a model of nuclear envelope membrane fusion and imply that modulating CLCC1 expression is a promising therapeutic...
In Stentor, a model in which regionalized differences in the patterning of cytoskeletal assemblies can be modulated by the regionalized localization of scaffolding proteins is suggested.
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