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G. Barba-Spaeth

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Open access Aug 2026

Dissociation kinetics and avidity gate SARS-CoV-2 neutralization by HR2 stem helix antibodies

It is shown that plasma IgG reactivity to this region remains rare, even after repeated antigen exposure, and kinetic and avidity constraints governing neutralization at the HR2 stem helix and position hr2.016 as a resilient therapeutic candidate.

Virginia Crivelli, Concetta Guerra, M. Abernathy et al. · 0 citations

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